Are the Elderly Being Dosed with Dangerous Antipsychotic Drugs? – IOTW Report

Are the Elderly Being Dosed with Dangerous Antipsychotic Drugs?

Zero Hedge: Antipsychotic medication was the subject of a ¨black box¨ warning, issued by the FDA in 2005 and then again, in 2008. The warnings, which stated that the drugs should not be given to those over sixty years of age, was largely ignored by the elder care industry and by prescribing doctors.   According to Psychiatry Online, “The prescribing labels of all antipsychotics are now required to carry a standard warning.”

 “The boxed warning will say that elderly patients with dementia-related psychosis and treated with antipsychotics have an increased risk of death,” said Thomas Laughren, M.D., director of the Division of Psychiatry Products at the FDA’s Center for Drug Evaluation and Research, at a June 16 press conference. The revised labels were to be finalized within 30 days of the mandate.

The first round of black box warnings, in 2005, were aimed at second generation antipsychotics, atypical antipsychotics, such as  Aripiprazole (Abilify), Asenapine (Saphris), Brexpiprazole (Rexulti), Cariprazine (Vraylar), Clozapine (Clozaril), Iloperidone (Fanapt), Lurasidone (Latuda), Olanzapine (Zyprexa), Paliperidone (Invega), and Quetiapine (Seroquel). The 2008 warning was extended to all antipsychotic medication, including first generation, including  Chlorpromazine (Thorazine), Fluphenazine (Prolixin), Haloperidol (Haldol), Loxapine (Loxitane), Perphenazine (Trilafon), Pimozide (Orap), Thiothixene (Navane), and Trifluoperazine (Stelazine). more

14 Comments on Are the Elderly Being Dosed with Dangerous Antipsychotic Drugs?

  1. Alzheimer’s and other dementias cause the brain to die. They as a disease are a death sentence. The effects on the patient can be devastating, including hallucinations, horrible anxiety and terror and other effects. I have seen very low doses of these drugs have profoundly positive results including in my own mother and sister-in-law. My mother was taking the lowest dose available for 2.5 years before she passed away from COPD caused by lifelong smoking and a brain cell death event that impacted her ability to properly manage oxygen levels (so no apparent connectionto these drugs). If these drugs lead to slightly reduced longevity while addressing the horrible mental impacts of the dementia, how exactly is that so horrible in a disease that is fatal, incurable, and progressively degenerating? I am absolutely no fan of bigPharma, and know that alternative solutions might be effective if introduced soon enough and if the patient is WILLING to try them (generally they are not). I cannot speak to the abuse of these drugs, the overprescription of them to achieve other control objectives, etc. but if used appropriately, they appear to have positive impacts.

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  2. Sadly a lot of these meds are prescribed to treat symptoms that caregivers find difficult but are natural actions within an elderly person and the doctors do it in the name of management. As long as our doctors (and the consumers of meds) target symptoms rather than diseases we will see the continued risks increase (with resulting destruction of kidneys, livers, and heart disorders).

    Thanks doc for being a part of the problem.

    I speak as a person getting ready to go on dialysis due to excessive medication intervention.

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  3. Obsolete – the reality of course is that caregivers, whether family or paid assistants, MUST be able to get these folks fed, bathed, clothed, etc without being harmed or the patients harming themselves. It the worst of diseases and we are now going through round two with yet another loved one. I am not just talking out my ass.

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  4. Back in the 90’s we had a very large medical group and their claim to fame was prescribing a psych drug for any and all medical problems. I had a bleeding stomach ulcer, went to see the doctor 3 times and he gave me prescriptions that made me worse. I went to the book store and got a pill ID book and discovered he was giving me antidepressants and not ulcer drugs.

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  5. There’s only about two of those medications that are used in low doses among the elderly now. Abilify and seroquel

    The majority of those quit being used in psychiatric hospitals in the 80s and 90s

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  6. After my mom was sent to a nursing home for rehab after she broke an arm in a fall, my brother went to her doctor with “proof” that she had dementia. The doctor ordered a couple of bands put on her arm to set off alarms if she went too close to a door. By the time I made the drive from central Texas to southeast Missouri to get her out of her faux mental commitment, the nursing staff had convinced the doctor to put her on “medication” to make her more docile. My brother had stopped driving down from St. Louisish a couple of months before, after he had cleaned out everything he wanted from her house.

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