Abstract
Background
Many studies have evaluated the use of hydroxychloroquine in COVID-19. Most retrospective observational studies demonstrate a benefit of using HCQ on mortality, but not most randomized clinical trials.
Methods
We analyzed raw data collected from a cohort of 30,423 patients with COVID-19 cared for at IHU Méditerranée Infection in Marseille France and extracted from the DRYAD open data platform. We performed univariate and multivariable logistic regressions with all-cause mortality within six weeks. Multivariable logistic regressions were adjusted for sex, age group (<50, 50–69, 70–89 and > 89 years), periods (or variants), and type of patient management.
Results
Among 30,202 patients for whom information on treatment was available, 191/23,172 (0.82%) patients treated with HCQ-AZ died, compared to 344/7030 (4.89%) who did not receive treatment with HCQ-AZ. HCQ-AZ therapy was associated with a lower mortality than treatment without HCQ-AZ (odds ratio (OR) 0.16; 95% confidence interval (CI), 0.14–0.19). After adjustment for sex, age, period, and patient management, HCQ-AZ was associated with a significantly lower mortality rate (adjusted OR (aOR) 0.55, 95% CI 0.45–0.68). On a subsample of 21,664 patients with available variant information, results remained robust after adjustment on sex, age, patient management and variant (aOR 0.55; 95% CI 0.44–0.69). On a subsample of 16,063 patients, HCQ-AZ was still associated with a significantly lower mortality rate (aOR 0.47, 95%CI 0.29–0.75) after adjustment for sex, age, period, patient management, vaccination status and comorbidities.
Conclusion
Analysis of this large online database showed that HCQ-AZ was consistently associated with the lowest mortality.
Ivermectin and HCQ worked. As did NOT being tested for covid in the first place. You were highly more likely to be killed if you had a positive test result.
Fauci lied people died. FAF
Is there anything about COVID and their response that wasn’t a lie?
Turns out that I am allergic to HCQ, gives me itchy blisters…. BUT not Ivermectin which has saved me a few times from infected coworkers.
FJB
Off topic.
Happy Birthday, Mr. Hat!
Hope you have a thousand more!
@ manbearpig TUESDAY, 14 NOVEMBER 2023, 1:30 AT 1:30 AM
Absolutely nothing whatsoever. It is exactly what I was saying it was by May of 2020. The Global Wasming/Climate Change model on an accelerated time line.
My wife and I tested positive at different times early last year. She had awful symptoms and mine were more mild, but lingering. Living in the free State of Florida, we were able to get a prescription for a weeks worth of HQC. After taking the prescription for just 48 hours, we both tested negative. She got the jab earlier & I did not.
Proud to remain a pureblood and not drinking the kool-aid. That voice who warned me in the beginning, is still warning me.
Per crazy-eyed Ann Barnhardt, I’ll stick with the injectable Ivermectin.
Thank you,
Very Much
Pretty easy to figure this one.
Tonic water contain HCQ. One cup a day will give you protection after several weeks. My daughter, son-in-law and wife would not take tonic water and they all came down with covid. The bad news was that I had to do all the cooking and cleaning while they recovered. I never got covid and just read iotwreport.com while not busy. HINT: mix it with Scotch, Bourbon, Rum or Tequila
Much more enjoyable than horse paste (ha ha ha)